1988: Degree in Biology at the University of Siena.
1995: Ph.D. in Biotechnology at the University of Siena.
2002-2007: Researcher in Biochemistry at the University of Siena, faculty of Science.
2008- : Associate Professor of Biochemistry at the University of Siena, faculty of Science.
1994-2014: Organizer with D. Hochstrasser and J.-C. Sanchez (University of Geneva) and V. Pallini (University of Siena) of all the 10 editions of the biennial international meeting “From Genome To Proteome”.
2011: Organizer with D. Hochstrasser and J.-C. Sanchez (University of Geneva) of the 10th Word Congress of the Human Proteome Organization (Geneva 4-7 Sept., 2011).
1994-2017: Invited speaker in 60 national and international congress and seminars.
1998- : Author of the SIENA-2DPAGE database (http://www.bio-mol.unisi.it/).
2000- : Member of the Italian Biochemistry and Molecular Biology Society.
2001-2013: Member of the editorial board of the international journal PROTEOMICS (Wiley InterScience).
2003-2007: Member of the editorial board of the international journal AMINO ACIDS, the Forum for Amino Acid and Protein Research (Springer).
2005-2011: Member of the Congress and Communication Committee of the EuPA (European Proteome Association).
2006-2013: Member of the editorial board of the international journal PROTEOMICS: Clinical Applications (Wiley InterScience).
2006-2013: Member of the tutorial board of the international journal PROTEOMICS: Practical Proteomics (Wiley InterScience).
2012-: Associate Editor of the international journal EuPA OPEN PROTEOMICS (Elsevier).
2003-2006: Vice president of the Italian Human Proteome Organization (IHUPO, http://www.hupo.it/).
2010-2015: Vice president of the Italian Proteomics Association (ItPA).
2011- : President of the Biological Science Degree Course of the University of Siena.
2012-2014: Member of the Executive Committee of the European Proteomic Association (EuPA) and Head of the Conference and Communication Committee.
Since 25 years, Prof. Luca Bini is active in the global approach to the study of proteins. He is internationally well known as contributors to the establishment of the concept of “proteome science”.
The main research activities were focused on proteome analysis of clinical specimens such as cells, biopsies and body fluids in different patho-physiological conditions (breast, stomach and lung cancer, lung fibrosis, acute phase, cellular differentiation and signalling, apoptosis, etc..) to identify multivariate prognostic/diagnostic markers. Prof. Bini is one of the major expert on 2D-immunoblotting coupled to high sensitivity chemiluminescent detection system to study sets of proteins sharing post-translational modifications (phosphorylation, oxidation) and to study the immunproteome of infectious disease, using patient sera. The research group is involved in the study of the immuneresponse in autoantigenic neurodegenerative pathologies, such as Multiple Sclerosis. The group headed by Prof. Bini is also active in the proteomic characterization of different myopathies, fibrotic and oncologic diseases and in the molecular characterization of some genetic diseases such as Cornelia de Lange and Osteogenesis imperfecta. The scientific activity is well documented by more than 400 articles (160 in- extenso, H-index: 30), focused on proteomics applications to the study of biomedicine, model organisms, plants and bacteria.