Indications and appropriateness of instrumental examinations in emergency medicine. The monitoring of critical patients. Management of patients with polypathology and polytherapy. To formulate a diagnostic and therapeutic process through motivated and pertinent decisions to real clinical situations, evaluating the relationships between risks, costs and benefits in order to define an overall management strategy for the individual patient that takes into account prevention, therapy and rehabilitation. Identify and apply to real or simulated clinical cases the sensitivity, specificity, diagnostic and prognostic value of signs, symptoms and laboratory parameters.