The topics of the problems and consequently the disciplinary contents of the course are obviously varied, but the main theme of the course is the acquisition of group work skills, critical thinking, problem solving, and above all knowledge of the sources of information in medicine starting from the structure, functioning and mode of use of the scientific literature. In this context, the course presents itself as an introduction to the Evidence-based Medicine, including sessions in the computer classroom and e-learning modules related to the scientific literature, the revision and publication mechanisms, the distortions introduced by the improper use of bibliometric indexes (such as the impact factor and citation index), the functioning of the main free bibliographic search engines (Pubmed and Scholar), clinical databases based on rapid access evidence (such as Dynamed, Up-to date and Essential Evidence plus), the bibliographic research strategies, the types of answers that can be answered (background question and foreground question or PICO), the difference between therapy questions, etiology. prognosis etc. All this is carried out through practical sessions within problem learning, thus promoting familiarization with both literature and the English language and with information technology and information technology in acontext of scientific medicine. context of scientific medicine.