PHARMACEUTICAL TECHNOLOGY: Quality concept, as applicable to National Formulary
Sterile delivery system: Introduction and concepts. Parenteral drugs: General requirements; Types and their formulation with reference to Pharmacopoeial monographs; Packaging components, types, factors influencing choice of containers. Containers and closures (glass, plastics and rubber) and their evaluation, form, fill, seal technology, evaluation of containers and closures including a mention of compatibility testing (to be covered more extensively under stability info). Processing of parenteral products by terminal sterilization, filtration sterilization followed by aseptic filling and by aseptic compounding. Validation of sterilization and process validation.
Ophthalmic products: anatomy and physiology of eye, general requirement / safety considerations, formulation, isotonicity adjustment, isotonicity calculation, manufacture, packaging. Drug stability: Freeze-drying and residual water determination. Modified drug release: Sustained and Controlled Drug Delivery Systems (Polymers used in drug delivery). Liposomes. transdermal Therapeutic Systems. Preparation for inhalation. Aerosols. Extracts. Orphan drugs. Generic drugs. Veterinary drugs
PHARMACEUTICAL SOCIO-ECONOMY: National Health Service. Introduction to pharmacoeconomy. Introduction to pharmaceutical marketing. International market of drugs.
Health, illness, disease concepts and economic evaluation.
The ethic and the role of the Pharmacy Board. The national and international organization of the regulatory system.