The course is divided into two parts: the first frames the general features of the art-city relationship, then the aspects and problems related to artistic interventions in the city, carried out in an international and national scenario over the last fifty years. Above all, we look at those artworks characterized by an evident creative planning integrated with the processes of renewal and urban expansion. The framework starts from the international scene, with the examples of Caracas (the University City), of Paris (La Défense), of Barcelona (from the interventions of Solans to the Maragal plan for the Olympics celebrated in 1992). The first part is completed with specific historical-critical readings addressed to the Italian debate and experiences, paying attention to the following topics: urban animations as 'new' bodies in the memory of the city; stories of creativity and negations from "Urban Field" in Como (1969) to "Christmas in Naples" (1970), to "Volterra 73", to the controversies that have affected Paladino's interventions in Positano (2002); types of territorial interventions from Fiumara d'Arte to installations in San Gimignano, Campo del Sole in Tuoro sul Trasimeno, the Museo en plein air of Lamezia Terme, the Hortus Conclusus of Benevento, the Giardino del Gigante di Cento, the stations of the Naples subway, the Paladino piazza in Vinci, the intervention by Ceroli in Florence, the Environmental Art Museum of Giffoni Sei Casali, the Metrò Napoli NordEst Mugnano station by Casciello. The second part is a study in a monographic sense, aimed at new urban realities, also in relation to the affirmation of a decorative taste of the city and the territory: the cases examined are the Plateau du Kierchberg in Luxembourg, the operation Arte in Pollino, the new Street Art interventions in Italy.