Basic cellular and biochemical knowledge on cell signaling and communications. Basic knowledge on antibody structure and function
Aim of the course is providing the molecular and cellular basis for understanding innovative diagnostic techniques and therapy approaches in oncology. The course is also aimed at making the students autonomous for collecting specific literature from dedicated scientific data bases, choosing updated papers for deepening the arguments discussed during the course, understanding scientific papers into details and exposing and discussing in an organized professional presentation with professor and colleagues.
Cell signaling in cancer cells. Cell signaling in immune system. Cancer and immune system. Molecular basis of cancer immunotherapy and targeted therapy. Morphogenic signaling in cancer. Cancer cell and extracellular matrix. In vivo imaging of cancer. Biomarkers. Nanomedicine in oncology. Monoclonal and recombinant antibody technology. Human monoclonal and recombinant antibodies in cancer therapy and diagnosis. Peptides for tumor targeting
Due to the highly innovative and application oriented subject there are no specific reference texts. Students will be provided with slides from the course with extensive legends and with specific references to scientific literature
Formal lessons, practical laboratory lessons, reading and discussion of scientific papers, which students should autonomously collect from dedicated scientific data bases and then discuss by a public presentation
Oral exam and a public presentation on topics related to the course program. Students should chose a topic, autonomously collect the specific literature and prepare a professional-like presentation
No further information