Knowledge of normal and pathological spermatogenesi and oogenesis, sperm and oocyte pathologies. Oxidative damage of gametes.
The spermatozoon from epididymis to oocytes: sperm maturation during epididymal transit, sperm capacitation, fertilizing ability acquisition in the female genital tract, acrosome reaction. Knowledge of the mechanisms involved in fertilization. Optical and electron microscopy of testis, ovary and human gametes. Fluorescence in situ hybridization applied to human gametes. Immunocytochemistry applied to human gametes