Basic knowledge of genetics and molecular biology
The main goal of this course is to describe at the molecular level, the structure of human genome, its evolution and the function of its elements and to provide a strong background of the main techniques currently used in molecular biology laboratories.
Analysis of genomes structure and genome projects.
Genomic databases and browsers for their analysis.
Human genome organization.
Coding genes: structure and evolution.
Non coding genes: structure and function.
Highly repetitive DNA: structure and function.
Comparative genomics and model organisms.
Genes and genomes evolution.
Human genetic variation.
DNA damages and repair mechanisms.
Main techniques of molecular biology
Genetica molecolare umana. T. Strachan, A. Read. ZANICHELLI
Dai geni ai Genomi. Principi ed applicazioni della tecnologia del DNA ricombinante. J.W. Dale e M. von Schantz.
Lectures and pratical training
The regular attendance is recommended.